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Illicit fentanyl use in the U.S. far higher than previously reported

May 10, 2025
in Health
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Extra People use illicit opioids equivalent to fentanyl than beforehand estimated, highlighting the necessity for higher strategies to grasp the depths of the opioid disaster, in accordance with a brand new research.

A survey of American adults discovered that 11% reported illicit opioid use throughout the previous 12 months and seven.5% reported use of illicitly produced fentanyl throughout the identical interval, charges which might be greater than 20 instances larger than estimates from a big federal research that yearly asks People about their use of illicit medication.

Researchers say the findings add to the proof that authorities counts could considerably underestimate illicit drug use and counsel that new strategies are mandatory to raised monitor a key metric in addressing the nation’s opioid disaster. The findings are printed within the journal JAMA Well being Discussion board.

Estimates of illicit opioid use are uncommon and usually can be found solely years after the data is collected, limiting our capacity to watch developments on a near-term foundation. Our research presents a way to rapidly and repeatedly monitor illicit opioid prevalence at low-cost.”


David Powell, research’s lead creator and senior economist at RAND

Initially pushed by prescription opioids, the opioid disaster within the U.S. transitioned to heroin within the early 2010s after which to illicitly-manufactured fentanyl just a few years later.

Because the opioid disaster continues to evolve and polysubstance deaths turn out to be more and more frequent, illegally manufactured fentanyl stays concerned in most overdose deaths. Regardless of the significance of illicit opioids within the present substance-use panorama, comparatively little is thought in regards to the prevalence of illicit opioid use.

The most important ongoing research that tracks illicit drug use is the Nationwide Survey on Drug Use and Well being. That research started asking about use of illicitly manufactured fentanyl solely in 2022, reporting that 0.3% of adults used the drug that 12 months.

Quite a few earlier research even have reported larger charges of illicit opioid use, difficult the accuracy of the federal estimate. Whereas researchers say the explanations for the variations are unclear, they counsel it could relate to the way in which the federal survey asks members about illicit opioid use.

This contains the truth that about half of the surveys within the federal depend are achieved in particular person, which can inhibit members from reporting illicit drug use. Researchers say extra work is required to grasp the rationale for the variations.

Researchers from RAND and the College of Southern California surveyed 1,515 American adults throughout June 2024 utilizing a big, consultant on-line panel of People. Contributors have been requested about use of non-prescription opioids throughout the previous 12 months, with heroin and illicitly-manufactured fentanyl given as examples.

A novel facet of the survey was asking members about whether or not they deliberately used illicit opioids, and whether or not they deliberately or unintentionally used illicitly manufactured fentanyl.

Amongst these surveyed, 7.7% reported intentional nonprescription opioid use, with one other 3.2% reporting unintentional nonprescription opioid use.

Most individuals who used nonprescription opioids reported illicit fentanyl use. The speed of intentional use of illicitly manufactured fentanyl was 4.9% whereas the speed of unintentional use of fentanyl was 2.6%.

Amongst respondents reporting nonprescription opioid use throughout the previous 12 months, 39% reported their first use of opioids concerned medicine prescribed to them, whereas 36% reported their first use concerned prescription opioids not prescribed to them. The remaining 25% answered that their first publicity to opioids concerned illicitly manufactured opioids.

“In the end, the information introduced right here needs to be handled as a substantive knowledge level for understanding and curbing the continued opioid disaster,” mentioned Mireille Jacobson, the research’s co-author and an economist on the College of Southern California. “Extra close to real-time data is required to guage not solely the place we’re within the epidemic, however, extra importantly, whether or not we’re making progress in reining it in.”
One limitation of the survey was using a web-based platform. Whereas much like nationwide charges when it comes to demographics, the surveyed inhabitants may very well be totally different in unobserved methods. The authors intend to re-examine their findings quickly, utilizing a survey platform extra strong to those issues.

Assist for the research was supplied by Arnold Ventures and the Nationwide Institutes of Well being’s Nationwide Institute on Drug Abuse below award numbers R21DA06011 and 2P50DA046351-06A1. The content material on this press launch is solely the accountability of the authors and doesn’t essentially signify the official views of the Nationwide Institutes of Well being.

RAND Well being Care promotes more healthy societies by bettering well being care techniques in america and different international locations.

Supply:

Journal reference:

Powell, D., & Jacobson, M. (2025). Estimates of Illicit Opioid Use within the US. JAMA Well being Discussion board. doi.org/10.1001/jamahealthforum.2025.0809.



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Tags: fentanylHigherillicitpreviouslyreportedU.S
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